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B-1a Cell Diversity: N-addition in B-1a immunoglobulin is determined by progenitor population and developmental location()

Natural antibodies produced by B-1a cells are required for immediate protection against infection. The protective capacity of natural antibodies is attributed to germ-line like structure, which includes the relative absence of N-region addition. Previous studies have shown B-1a cell immunoglobulin f...

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Bibliographic Details
Main Authors: Holodick, Nichol E., Vizconde, Teresa, Rothstein, Thomas L.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3966105/
https://ncbi.nlm.nih.gov/pubmed/24477911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300247
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