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Antigen Receptor Specificity and Cell Location Influence the Diversification and Selection of the B-1a Cell Pool with Age

B-1a cells provide immediate and essential protection from infection through production of natural immunoglobulin, which is germline-like due to minimal insertion of N-region additions. We have previously demonstrated peritoneal B-1a cell derived phosphorylcholine (PC)-specific and total IgM moves a...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Tsuji, Naomi, Rothstein, Thomas L., Holodick, Nichol E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7507122/
https://ncbi.nlm.nih.gov/pubmed/32561570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1901302
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