Diversification of the antigen-specific T cell receptor repertoire after varicella zoster vaccination

Diversity and size of the antigen-specific T cell receptor (TCR) repertoire are two critical determinants for successful control of chronic infection. Varicella zoster virus (VZV) that establishes latency during childhood is able to escape control mechanisms, in particular with increasing age. We ex...

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Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Qi, Qian, Cavanagh, Mary M., Le Saux, Sabine, NamKoong, Hong, Kim, Chulwoo, Turgano, Emerson, Liu, Yi, Wang, Chen, Mackey, Sally, Swan, Gary E., Dekker, Cornelia L., Olshen, Richard A., Boyd, Scott D., Weyand, Cornelia M., Tian, Lu, Goronzy, Jörg J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4878824/
https://ncbi.nlm.nih.gov/pubmed/27030598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaf1725
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