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Defective T Memory Cell Differentiation after Varicella Zoster Vaccination in Older Individuals

Vaccination with attenuated live varicella zoster virus (VZV) can prevent zoster reactivation, but protection is incomplete especially in an older population. To decipher the molecular mechanisms underlying variable vaccine responses, T- and B-cell responses to VZV vaccination were examined in indiv...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Qi, Qian, Cavanagh, Mary M., Le Saux, Sabine, Wagar, Lisa E., Mackey, Sally, Hu, Jinyu, Maecker, Holden, Swan, Gary E., Davis, Mark M., Dekker, Cornelia L., Tian, Lu, Weyand, Cornelia M., Goronzy, Jörg J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5072604/
https://ncbi.nlm.nih.gov/pubmed/27764254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005892
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