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Defective T Memory Cell Differentiation after Varicella Zoster Vaccination in Older Individuals

Vaccination with attenuated live varicella zoster virus (VZV) can prevent zoster reactivation, but protection is incomplete especially in an older population. To decipher the molecular mechanisms underlying variable vaccine responses, T- and B-cell responses to VZV vaccination were examined in indiv...

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Détails bibliographiques
Publié dans:PLoS Pathog
Auteurs principaux: Qi, Qian, Cavanagh, Mary M., Le Saux, Sabine, Wagar, Lisa E., Mackey, Sally, Hu, Jinyu, Maecker, Holden, Swan, Gary E., Davis, Mark M., Dekker, Cornelia L., Tian, Lu, Weyand, Cornelia M., Goronzy, Jörg J.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5072604/
https://ncbi.nlm.nih.gov/pubmed/27764254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005892
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