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Immunoglobulin secretion by B1 cells: Differential intensity and IRF4-dependence of spontaneous IgM secretion by peritoneal and splenic B1 cells

Peritoneal B1 cells are typified by spontaneous, constitutive secretion of IgM natural antibody, detected by ELISPOT assay, among other means. Recently, this key characteristic has been called into question, a reason for which we evaluated the integrity of IgM(+) ELISPOT spots. We found that fixed B...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Holodick, Nichol E., Tumang, Joseph R., Rothstein, Thomas L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139744/
https://ncbi.nlm.nih.gov/pubmed/21061433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201040545
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