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Continual Signaling Is Responsible for Constitutive ERK Phosphorylation in B-1a Cells

B-1a cells constitutively express phosphorylated, activated ERK, but the origin of pERK in B-1 cells has not been determined. To address this issue, we examined specific mediators of intracellular signaling in unmanipulated B-1a cells. We found that constitutive pERK was rapidly lost from B-1a cells...

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Auteurs principaux: Holodick, Nichol E., Tumang, Joseph R., Rothstein, Thomas L.
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770333/
https://ncbi.nlm.nih.gov/pubmed/19592097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2009.06.011
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