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Atypical Response of B-1 Cells to BCR Ligation: A Speculative Model

Peritoneal B-1a cells manifest unusual signaling characteristics that distinguish them from splenic B-2 cells. These include the failure of BCR engagement to trigger NF-κB activation and DNA replication. Despite extensive study, a clear explanation for these characteristics has not emerged. Here we...

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Bibliografiske detaljer
Main Authors: Holodick, Nichol E., Rothstein, Thomas L.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3864358/
https://ncbi.nlm.nih.gov/pubmed/24379817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00457
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