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Fluorescent labeling of tRNA dihydrouridine residues: Mechanism and distribution

Dihydrouridine (DHU) positions within tRNAs have long been used as sites to covalently attach fluorophores, by virtue of their unique chemical reactivity toward reduction by NaBH(4), their abundance within prokaryotic and eukaryotic tRNAs, and the biochemical functionality of the labeled tRNAs so pr...

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Detalhes bibliográficos
Main Authors: Kaur, Jaskiran, Raj, Monika, Cooperman, Barry S.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138574/
https://ncbi.nlm.nih.gov/pubmed/21628433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2670811
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