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Allosteric vs. spontaneous exit-site (E-site) tRNA dissociation early in protein synthesis
During protein synthesis, deacylated transfer RNAs leave the ribosome via an exit (E) site after mRNA translocation. How the ribosome regulates tRNA dissociation and whether functional linkages between the aminoacyl (A) and E sites modulate the dynamics of protein synthesis have long been debated. U...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3193197/ https://ncbi.nlm.nih.gov/pubmed/21969541 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1106999108 |
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