QUANTIFYING ELONGATION RHYTHM DURING FULL-LENGTH PROTEIN SYNTHESIS

Pauses regulate the rhythm of ribosomal protein synthesis. Mutations disrupting even minor pauses can give rise to improperly formed proteins and human disease. Such minor pauses are difficult to characterize by ensemble methods, but can be readily examined by single-molecule (sm) approaches. Here w...

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Main Authors: Rosenblum, Gabriel, Chen, Chunlai, Kaur, Jaskiran, Cui, Xiaonan, Zhang, Haibo, Asahara, Haruichi, Chong, Shaorong, Smilansky, Zeev, Goldman, Yale E., Cooperman, Barry S.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2013
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Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3768011/
https://ncbi.nlm.nih.gov/pubmed/23822614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja405205c
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