Loading...

Preparation of a Series of 5-Methyl-3-(substituted)-[1,2,4]triazines

Procedures for the synthesis of thirty-six 5-methyl-3-(substituted)-[1,2,4]triazines have been described. These compounds were evaluated for antagonism at metabotropic glutamate receptor subtype 5. Two compounds, 5b and 3c, were determined to be low micromolar inhibitors of mGluR5.

Na minha lista:
Bibliografiske detaljer
Main Authors: Gichinga, Moses G., Olson, Jeremy P., Butala, Elizabeth, Gilmour, Brian P., Navarro, Hernán H., Carroll, F. Ivy
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138555/
https://ncbi.nlm.nih.gov/pubmed/21779134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2011.04.075
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!