Caricamento...
A ubiquitin ligase-associated chaperone holdase maintains polypeptides in soluble states for proteasome degradation
Endoplasmic reticulum-associated degradation (ERAD) employs membrane-bound ubiquitin ligases and the translocation-driving ATPase p97 to retrotranslocate misfolded proteins for proteasomal degradation. How retrotranslocated polypeptides bearing exposed hydrophobic motifs or transmembrane domains (TM...
Salvato in:
| Autori principali: | , , , , , |
|---|---|
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3138499/ https://ncbi.nlm.nih.gov/pubmed/21636303 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.05.010 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|