Physical association of ubiquitin ligases and the 26S proteasome
The ubiquitin (Ub) system recognizes degradation signals of the target proteins through the E3 components of E3-E2 Ub ligases. A targeted substrate bears a covalently linked multi-Ub chain and is degraded by the ATP-dependent 26S proteasome, which consists of the 20S core protease and two 19S partic...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2000
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15957/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10688918/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.060025497 |
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