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Physical association of ubiquitin ligases and the 26S proteasome

The ubiquitin (Ub) system recognizes degradation signals of the target proteins through the E3 components of E3-E2 Ub ligases. A targeted substrate bears a covalently linked multi-Ub chain and is degraded by the ATP-dependent 26S proteasome, which consists of the 20S core protease and two 19S partic...

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Xie, Youming, Varshavsky, Alexander
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2000
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15957/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10688918/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.060025497
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