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Physical association of ubiquitin ligases and the 26S proteasome

The ubiquitin (Ub) system recognizes degradation signals of the target proteins through the E3 components of E3-E2 Ub ligases. A targeted substrate bears a covalently linked multi-Ub chain and is degraded by the ATP-dependent 26S proteasome, which consists of the 20S core protease and two 19S partic...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Xie, Youming, Varshavsky, Alexander
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The National Academy of Sciences 2000
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC15957/
https://ncbi.nlm.nih.gov/pubmed/10688918
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