Reduced virulence of a defined pneumolysin-negative mutant of Streptococcus pneumoniae.
Insertion-duplication mutagenesis was used to construct a pneumolysin-negative derivative of Streptococcus pneumoniae. This was achieved by first transforming the nonencapsulated strain Rx1 with a derivative of the vector pVA891 carrying a 690-base-pair DNA fragment from the middle of the pneumolysi...
Kaydedildi:
| Yayımlandı: | Infect Immun |
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| Asıl Yazarlar: | , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Microbiology (ASM)
1989
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC313838/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2731982/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.57.7.2037-2042.1989 |
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