Inhibitory Effects of Glycyrrhetinic Acid on DNA Polymerase and Inflammatory Activities

We investigated the inhibitory effect of three glycyrrhizin derivatives, such as Glycyrrhizin (compound 1), dipotassium glycyrrhizate (compound 2) and glycyrrhetinic acid (compound 3), on the activity of mammalian pols. Among these derivatives, compound 3 was the strongest inhibitor of mammalian pol...

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Bibliographic Details
Main Authors: Ishida, Tsukasa, Mizushina, Yoshiyuki, Yagi, Saori, Irino, Yasuhiro, Nishiumi, Shin, Miki, Ikuya, Kondo, Yasuyuki, Mizuno, Shigeto, Yoshida, Hiromi, Azuma, Takeshi, Yoshida, Masaru
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138047/
https://ncbi.nlm.nih.gov/pubmed/21785649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/650514
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