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The Inhibitory Action of Kohamaic Acid A Derivatives on Mammalian DNA Polymerase β

We previously isolated a novel natural product, designated kohamaic acid A (KA-A, compound 1), as an inhibitor of the first cleavage of fertilized sea urchin eggs, and found that this compound could selectively inhibit the activities of mammalian DNA polymerases (pols). In this paper, we investigate...

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Publicado en:Molecules
Main Authors: Mizushina, Yoshiyuki, Manita, Daisuke, Takeuchi, Toshifumi, Sugawara, Fumio, Kumamoto-Yonezawa, Yuko, Matsui, Yuki, Takemura, Masaharu, Sasaki, Mitsuru, Yoshida, Hiromi, Takikawa, Hirosato
Formato: Artigo
Idioma:Inglês
Publicado: Molecular Diversity Preservation International 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6253949/
https://ncbi.nlm.nih.gov/pubmed/19127241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules14010102
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