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The Inhibitory Action of Kohamaic Acid A Derivatives on Mammalian DNA Polymerase β

We previously isolated a novel natural product, designated kohamaic acid A (KA-A, compound 1), as an inhibitor of the first cleavage of fertilized sea urchin eggs, and found that this compound could selectively inhibit the activities of mammalian DNA polymerases (pols). In this paper, we investigate...

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Publicado no:Molecules
Main Authors: Mizushina, Yoshiyuki, Manita, Daisuke, Takeuchi, Toshifumi, Sugawara, Fumio, Kumamoto-Yonezawa, Yuko, Matsui, Yuki, Takemura, Masaharu, Sasaki, Mitsuru, Yoshida, Hiromi, Takikawa, Hirosato
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6253949/
https://ncbi.nlm.nih.gov/pubmed/19127241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules14010102
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