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The relationship between the molecular structure of natural acetogenins and their inhibitory activities which affect DNA polymerase, DNA topoisomerase and human cancer cell growth

Acetogenins from the Annonaceous plant are a fatty acid-derived natural product. Chemically synthesized natural acetogenins, such as mucocin (compound 1), jimenezin (compound 2), muconin (compound 4), pyranicin (compound 5) and pyragonicin (compound 6) were investigated. Concomitantly, 19-epi jimene...

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Main Authors: MATSUI, YUKI, TAKEUCHI, TOSHIFUMI, KUMAMOTO-YONEZAWA, YUKO, TAKEMURA, MASAHARU, SUGAWARA, FUMIO, YOSHIDA, HIROMI, MIZUSHINA, YOSHIYUKI
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3490394/
https://ncbi.nlm.nih.gov/pubmed/23136587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm_00000004
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