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Effects of Intermediates between Vitamins K(2) and K(3) on Mammalian DNA Polymerase Inhibition and Anti-Inflammatory Activity
Previously, we reported that vitamin K(3) (VK(3)), but not VK(1) or VK(2) (=MK-4), inhibits the activity of human DNA polymerase γ (pol γ). In this study, we chemically synthesized three intermediate compounds between VK(2) and VK(3), namely MK-3, MK-2 and MK-1, and investigated the inhibitory effec...
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| Main Authors: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Molecular Diversity Preservation International (MDPI)
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3083694/ https://ncbi.nlm.nih.gov/pubmed/21541047 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms12021115 |
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