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Dietary fish oil promotes colonic apoptosis and mitochondrial proton leak in oxidatively stressed mice

An alteration of mitochondrial function can result in disruption of redox homeostasis, and is associated with abnormal cancer cell growth. Manganese superoxide dismutase (SOD2) and glutathione peroxidase 4 (Gpx4) are two of the most important antioxidant defense enzymes that protect cells against ox...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Fan, Yang-Yi, Ran, Qitao, Toyokuni, Shinya, Okazaki, Yasumasa, Callaway, Evelyn S., Lupton, Joanne R., Chapkin, Robert S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137683/
https://ncbi.nlm.nih.gov/pubmed/21490130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-10-0368
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