A chemoprotective fish oil/pectin diet enhances apoptosis via Bcl-2 promoter methylation in rat azoxymethane-induced carcinomas

We have demonstrated that diets containing fish oil and pectin (FO/P) reduce colon tumor incidence relative to control (corn oil and cellulose [CO/C]) in part by inducing apoptosis of DNA-damaged colon cells. Relative to FO/P, CO/C promotes colonocyte expression of the antiapoptotic modulator, Bcl-2...

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Detalhes bibliográficos
Main Authors: Cho, Youngmi, Turner, Nancy D, Davidson, Laurie A, Chapkin, Robert S, Carroll, Raymond J, Lupton, Joanne R
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3999967/
https://ncbi.nlm.nih.gov/pubmed/23354397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1258/ebm.2012.012244
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