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Colon cancer cell apoptosis is induced by combined exposure to the n-3 fatty acid docosahexaenoic acid and butyrate through promoter methylation

DNA methylation and histone acetylation contribute to the transcriptional regulation of genes involved in apoptosis. We have demonstrated that docosahexaenoic acid (DHA, 22:6 n-3) and butyrate enhance colonocyte apoptosis. To determine if DHA and/or butyrate elevate apoptosis through epigenetic mech...

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Bibliografski detalji
Glavni autori: Cho, Youngmi, Turner, Nancy D, Davidson, Laurie A, Chapkin, Robert S, Carroll, Raymond J, Lupton, Joanne R
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3999970/
https://ncbi.nlm.nih.gov/pubmed/24495951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370213514927
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