Immunomodulatory action of dietary fish oil and targeted deletion of intestinal epithelial cell PPARδ in inflammation-induced colon carcinogenesis

The ligand-activated transcription factor peroxisome proliferator-activated receptor (PPAR)-δ is highly expressed in colonic epithelial cells; however, the role of PPARδ ligands, such as fatty acids, in mucosal inflammation and malignant transformation has not been clarified. Recent evidence suggest...

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Detalhes bibliográficos
Main Authors: Monk, Jennifer M., Kim, Wooki, Callaway, Evelyn, Turk, Harmony F., Foreman, Jennifer E., Peters, Jeffrey M., He, Weimin, Weeks, Brad, Alaniz, Robert C., McMurray, David N., Chapkin, Robert S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Liver and Biliary Tract
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3345959/
https://ncbi.nlm.nih.gov/pubmed/21940900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00315.2011
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