Dietary fish oil promotes colonic apoptosis and mitochondrial proton leak in oxidatively stressed mice

An alteration of mitochondrial function can result in disruption of redox homeostasis, and is associated with abnormal cancer cell growth. Manganese superoxide dismutase (SOD2) and glutathione peroxidase 4 (Gpx4) are two of the most important antioxidant defense enzymes that protect cells against ox...

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Bibliographic Details
Main Authors: Fan, Yang-Yi, Ran, Qitao, Toyokuni, Shinya, Okazaki, Yasumasa, Callaway, Evelyn S., Lupton, Joanne R., Chapkin, Robert S.
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137683/
https://ncbi.nlm.nih.gov/pubmed/21490130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-10-0368
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