Dopaminergic Pathway Reconstruction by Akt/Rheb-Induced Axon Regeneration

OBJECTIVE: A prevailing concept in neuroscience has been that the adult mammalian central nervous system is incapable of restorative axon regeneration. Recent evidence, however, has suggested that reactivation of intrinsic cellular programs regulated by Akt/mTor signaling may restore this ability. M...

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Main Authors: Kim, Sang Ryong, Chen, Xiqun, Oo, Tinmarla F., Kareva, Tatyana, Yarygina, Olga, Wang, Chuansong, During, Matthew, Kholodilov, Nikolai, Burke, Robert E.
Format: Artigo
Language:Inglês
Published: 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137673/
https://ncbi.nlm.nih.gov/pubmed/21437936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.22383
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