Akt Suppresses Retrograde Degeneration of Dopaminergic Axons by Inhibition of Macroautophagy

Axon degeneration is a hallmark of neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. Such degeneration is not a passive event but rather an active process mediated by mechanisms that are distinct from the canonical pathways of programmed cell death that med...

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Bibliographische Detailangaben
Hauptverfasser: Cheng, Hsiao-Chun, Kim, Sang Ryong, Oo, Tinmarla F., Kareva, Tatyana, Yarygina, Olga, Rzhetskaya, Margarita, Wang, Chuansong, During, Matthew, Talloczy, Zsolt, Tanaka, Keiji, Komatsu, Masaaki, Kobayashi, Kazuto, Okano, Hideyuki, Kholodilov, Nikolai, Burke, Robert E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2011
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075005/
https://ncbi.nlm.nih.gov/pubmed/21307249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5519-10.2011
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