Akt Suppresses Retrograde Degeneration of Dopaminergic Axons by Inhibition of Macroautophagy

Axon degeneration is a hallmark of neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. Such degeneration is not a passive event but rather an active process mediated by mechanisms that are distinct from the canonical pathways of programmed cell death that med...

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Autores principales: Cheng, Hsiao-Chun, Kim, Sang Ryong, Oo, Tinmarla F., Kareva, Tatyana, Yarygina, Olga, Rzhetskaya, Margarita, Wang, Chuansong, During, Matthew, Talloczy, Zsolt, Tanaka, Keiji, Komatsu, Masaaki, Kobayashi, Kazuto, Okano, Hideyuki, Kholodilov, Nikolai, Burke, Robert E.
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2011
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075005/
https://ncbi.nlm.nih.gov/pubmed/21307249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5519-10.2011
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