Akt Suppresses Retrograde Degeneration of Dopaminergic Axons by Inhibition of Macroautophagy

Axon degeneration is a hallmark of neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. Such degeneration is not a passive event but rather an active process mediated by mechanisms that are distinct from the canonical pathways of programmed cell death that med...

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Autors principals: Cheng, Hsiao-Chun, Kim, Sang Ryong, Oo, Tinmarla F., Kareva, Tatyana, Yarygina, Olga, Rzhetskaya, Margarita, Wang, Chuansong, During, Matthew, Talloczy, Zsolt, Tanaka, Keiji, Komatsu, Masaaki, Kobayashi, Kazuto, Okano, Hideyuki, Kholodilov, Nikolai, Burke, Robert E.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2011
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075005/
https://ncbi.nlm.nih.gov/pubmed/21307249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5519-10.2011
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