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Akt Suppresses Retrograde Degeneration of Dopaminergic Axons by Inhibition of Macroautophagy

Axon degeneration is a hallmark of neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. Such degeneration is not a passive event but rather an active process mediated by mechanisms that are distinct from the canonical pathways of programmed cell death that med...

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Main Authors: Cheng, Hsiao-Chun, Kim, Sang Ryong, Oo, Tinmarla F., Kareva, Tatyana, Yarygina, Olga, Rzhetskaya, Margarita, Wang, Chuansong, During, Matthew, Talloczy, Zsolt, Tanaka, Keiji, Komatsu, Masaaki, Kobayashi, Kazuto, Okano, Hideyuki, Kholodilov, Nikolai, Burke, Robert E.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Society for Neuroscience 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075005/
https://ncbi.nlm.nih.gov/pubmed/21307249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5519-10.2011
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