Age and α-Synuclein Expression Interact to Reveal a Dependence of Dopaminergic Axons On Endogenous Akt/PKB Signaling

The mechanisms underlying the chronic neurodegeneration that occurs in Parkinson’s disease (PD) are unknown. One emerging hypothesis is that neural systems deteriorate and eventually degenerate due to a primary failure of either extrinsic neurotrophic support or the intrinsic cellular pathways that...

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Библиографические подробности
Главные авторы: Kim, Sang Ryong, Ries, Vincent, Cheng, Hsiao-Chun, Kareva, Tatyana, Oo, Tinmarla F., Yu, W. Haung, Duff, Karen, Kholodilov, Nikolai, Burke, Robert E.
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3167022/
https://ncbi.nlm.nih.gov/pubmed/21782946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2011.07.003
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