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Astrocytes as determinants of disease progression in inherited ALS
Dominant mutations in superoxide dismutase cause amyotrophic lateral sclerosis (ALS), an adult-onset neurodegenerative disease characterized by loss of motor neurons. Using mice carrying a deletable mutant gene, diminished mutant expression in astrocytes did not affect onset, but delayed microglial...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3137510/ https://ncbi.nlm.nih.gov/pubmed/18246065 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn2047 |
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