D-Glucuronyl C5-epimerase suppresses small-cell lung cancer cell proliferation in vitro and tumour growth in vivo

BACKGROUND: D-Glucuronyl C5-epimerase (GLCE) is a key enzyme involved in the biosynthesis of heparan sulphate proteoglycans, which has an important role in cell–cell and cell–matrix interactions and signalling. Decreased GLCE expression in human breast tumours and its anti-proliferative effects in b...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Grigorieva, E V, Prudnikova, T Y, Domanitskaya, N V, Mostovich, L A, Pavlova, T V, Kashuba, V I, Zabarovsky, E R
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2011
Schlagworte:
Translational Therapeutics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137399/
https://ncbi.nlm.nih.gov/pubmed/21654676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.170
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge