The TCF4/β-catenin pathway and chromatin structure cooperate to regulate D-glucuronyl C5-epimerase expression in breast cancer

D-glucuronyl C5-epimerase (GLCE) is a potential tumor-suppressor gene involved in heparan sulfate biosynthesis. GLCE expression is significantly decreased in breast tumors; however, the underlying molecular mechanisms remain unclear. This study examined the possible epigenetic mechanisms for GLCE in...

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Detalhes bibliográficos
Main Authors: Mostovich, Luydmila A., Prudnikova, Tatiana Y., Kondratov, Aleksandr G., Gubanova, Natalya V., Kharchenko, Olga A., Kutsenko, Olesya S., Vavilov, Pavel V., Haraldson, Klas, Kashuba, Vladimir I., Ernberg, Ingemar, Zabarovsky, Eugene R., Grigorieva, Elvira V.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427288/
https://ncbi.nlm.nih.gov/pubmed/22805760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.21199
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