The TCF4/β-catenin pathway and chromatin structure cooperate to regulate D-glucuronyl C5-epimerase expression in breast cancer

D-glucuronyl C5-epimerase (GLCE) is a potential tumor-suppressor gene involved in heparan sulfate biosynthesis. GLCE expression is significantly decreased in breast tumors; however, the underlying molecular mechanisms remain unclear. This study examined the possible epigenetic mechanisms for GLCE in...

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Autors principals: Mostovich, Luydmila A., Prudnikova, Tatiana Y., Kondratov, Aleksandr G., Gubanova, Natalya V., Kharchenko, Olga A., Kutsenko, Olesya S., Vavilov, Pavel V., Haraldson, Klas, Kashuba, Vladimir I., Ernberg, Ingemar, Zabarovsky, Eugene R., Grigorieva, Elvira V.
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2012
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427288/
https://ncbi.nlm.nih.gov/pubmed/22805760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.21199
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