Antiproliferative effect of D-glucuronyl C5-epimerase in human breast cancer cells

BACKGROUND: D-glucuronyl C5-epimerase (GLCE) is one of the key enzymes in the biosynthesis of heparansulfate proteoglycans. Down-regulation of GLCE expression in human breast tumours suggests a possible involvement of the gene in carcinogenesis. In this study, an effect of GLCE ectopic expression on...

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Hauptverfasser: Prudnikova, Tatiana Y, Mostovich, Liudmila A, Domanitskaya, Natalia V, Pavlova, Tatiana V, Kashuba, Vladimir I, Zabarovsky, Eugene R, Grigorieva, Elvira V
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2010
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Primary Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936283/
https://ncbi.nlm.nih.gov/pubmed/20723247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-10-27
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