Bordetella pertussis adenylate cyclase toxin: intoxication of host cells by bacterial invasion.

Bordetella pertussis produces extracytoplasmic adenylate cyclase toxin (AC toxin) which penetrates target cells and, upon activation by host calmodulin, generates high levels of intracellular cyclic AMP (cAMP). As a result, bactericidal functions of immune effector cells are impaired. Since a consid...

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Bibliografische Detailangaben

Veröffentlicht in:	Infect Immun
Hauptverfasser:	Mouallem, M, Farfel, Z, Hanski, E
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1990
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC313725/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2172167/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.58.11.3759-3764.1990
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