Bordetella pertussis adenylate cyclase toxin: intoxication of host cells by bacterial invasion.

Bordetella pertussis produces extracytoplasmic adenylate cyclase toxin (AC toxin) which penetrates target cells and, upon activation by host calmodulin, generates high levels of intracellular cyclic AMP (cAMP). As a result, bactericidal functions of immune effector cells are impaired. Since a consid...

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Pubblicato in:	Infect Immun
Autori principali:	Mouallem, M, Farfel, Z, Hanski, E
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1990
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC313725/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2172167/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.58.11.3759-3764.1990
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