Bordetella pertussis adenylate cyclase toxin: intoxication of host cells by bacterial invasion.

Bordetella pertussis produces extracytoplasmic adenylate cyclase toxin (AC toxin) which penetrates target cells and, upon activation by host calmodulin, generates high levels of intracellular cyclic AMP (cAMP). As a result, bactericidal functions of immune effector cells are impaired. Since a consid...

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Bibliografski detalji

Izdano u:	Infect Immun
Glavni autori:	Mouallem, M, Farfel, Z, Hanski, E
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 1990
Teme:	Research Article
Online pristup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC313725/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2172167/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.58.11.3759-3764.1990
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