Bordetella pertussis adenylate cyclase toxin: intoxication of host cells by bacterial invasion.

Bordetella pertussis produces extracytoplasmic adenylate cyclase toxin (AC toxin) which penetrates target cells and, upon activation by host calmodulin, generates high levels of intracellular cyclic AMP (cAMP). As a result, bactericidal functions of immune effector cells are impaired. Since a consid...

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Bibliografische gegevens

Gepubliceerd in:	Infect Immun
Hoofdauteurs:	Mouallem, M, Farfel, Z, Hanski, E
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	American Society for Microbiology (ASM) 1990
Onderwerpen:	Research Article
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC313725/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2172167/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.58.11.3759-3764.1990
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