Bordetella pertussis adenylate cyclase toxin: intoxication of host cells by bacterial invasion.

Bordetella pertussis produces extracytoplasmic adenylate cyclase toxin (AC toxin) which penetrates target cells and, upon activation by host calmodulin, generates high levels of intracellular cyclic AMP (cAMP). As a result, bactericidal functions of immune effector cells are impaired. Since a consid...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Mouallem, M, Farfel, Z, Hanski, E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC313725/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2172167/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.58.11.3759-3764.1990
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