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Cell synchronization by inhibitors of DNA replication induces replication stress and DNA damage response: analysis by flow cytometry
Cell synchronization is often achieved by inhibition of DNA replication. The cells cultured in the presence of such inhibitors as hydroxyurea, aphidicolin or thymidine become arrested at the entrance to S-phase and upon release from the block they synchronously progress through S, G(2) and M. We rec...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3137244/ https://ncbi.nlm.nih.gov/pubmed/21755443 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61779-182-6_6 |
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