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Analysis of Individual Molecular Events of DNA Damage Response by Flow and Image Assisted Cytometry

This chapter describes molecular mechanisms of DNA damage response (DDR) and presents flow- and image-assisted cytometric approaches to assess these mechanisms and measure the extent of DDR in individual cells. DNA damage was induced by cell treatment with oxidizing agents, UV light, DNA topoisomera...

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Detalhes bibliográficos
Main Authors: Darzynkiewicz, Zbigniew, Traganos, Frank, Zhao, Hong, Halicka, H. Dorota, Skommer, Joanna, Wlodkowic, Donald
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3132181/
https://ncbi.nlm.nih.gov/pubmed/21722802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-385493-3.00006-1
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