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Cell synchronization by inhibitors of DNA replication induces replication stress and DNA damage response: analysis by flow cytometry

Cell synchronization is often achieved by inhibition of DNA replication. The cells cultured in the presence of such inhibitors as hydroxyurea, aphidicolin or thymidine become arrested at the entrance to S-phase and upon release from the block they synchronously progress through S, G(2) and M. We rec...

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書誌詳細
主要な著者: Darzynkiewicz, Zbigniew, Halicka, H. Dorota, Zhao, Hong
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137244/
https://ncbi.nlm.nih.gov/pubmed/21755443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61779-182-6_6
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