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Cell synchronization by inhibitors of DNA replication induces replication stress and DNA damage response: analysis by flow cytometry

Cell synchronization is often achieved by inhibition of DNA replication. The cells cultured in the presence of such inhibitors as hydroxyurea, aphidicolin or thymidine become arrested at the entrance to S-phase and upon release from the block they synchronously progress through S, G(2) and M. We rec...

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Detalhes bibliográficos
Main Authors: Darzynkiewicz, Zbigniew, Halicka, H. Dorota, Zhao, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137244/
https://ncbi.nlm.nih.gov/pubmed/21755443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61779-182-6_6
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