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Structural Basis for Retinoic X Receptor Repression on the Tetramer
Retinoic X receptor (RXR) is a master nuclear receptor in the processes of cell development and homeostasis. Unliganded RXR exists in an autorepressed tetramer, and agonists can induce RXR dimerization and coactivator recruitment for activation. However, the molecular mechanisms involving the corepr...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3137034/ https://ncbi.nlm.nih.gov/pubmed/21613212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.245498 |
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