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Functional Asymmetry for the Active Sites of Linked 5-Aminolevulinate Synthase and 8-Amino-7-Oxononanoate Synthase
5-Aminolevulinate synthase (ALAS) and 8-amino-7-oxononanoate synthase (AONS) are homodimeric members of the α-oxoamine synthase family of pyridoxal 5′-phosphate (PLP)-dependent enzymes. Previously, linking two ALAS subunits into a single polypeptide chain dimer yielded an enzyme (ALAS/ALAS) with a s...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3136873/ https://ncbi.nlm.nih.gov/pubmed/21600186 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2011.05.002 |
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