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Transient State Kinetic Investigation of 5-Aminolevulinate Synthase Reaction Mechanism
5-Aminolevulinate synthase (ALAS), a pyridoxal 5′-phosphate-dependent enzyme, catalyzes the first, and regulatory, step of the heme biosynthetic pathway in nonplant eukaryotes and some bacteria. 5-Aminolevulinate synthase is a dimeric protein having an ordered kinetic mechanism with glycine binding...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2002
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3733378/ https://ncbi.nlm.nih.gov/pubmed/12191993 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M203584200 |
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