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Long Patch Base Excision Repair Compensates for DNA Polymerase β Inactivation by the C4′-Oxidized Abasic Site
The C4′-oxidized abasic site (C4-AP), which is produced by a variety of damaging agents has significant consequences on DNA. The lesion is highly mutagenic and reactive, resulting in interstrand cross-links. The base excision repair of DNA containing independently generated C4-AP was examined. C4-AP...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2010
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3136615/ https://ncbi.nlm.nih.gov/pubmed/21155533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi1017667 |
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