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Long Patch Base Excision Repair Compensates for DNA Polymerase β Inactivation by the C4′-Oxidized Abasic Site

The C4′-oxidized abasic site (C4-AP), which is produced by a variety of damaging agents has significant consequences on DNA. The lesion is highly mutagenic and reactive, resulting in interstrand cross-links. The base excision repair of DNA containing independently generated C4-AP was examined. C4-AP...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Jacobs, Aaron C., Kreller, Cortney R., Greenberg, Marc M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136615/
https://ncbi.nlm.nih.gov/pubmed/21155533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi1017667
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