The pro-longevity gene FoxO3 is a direct target of the p53 tumor suppressor

FoxO transcription factors play a conserved role in longevity and act as tissue-specific tumor suppressors in mammals. Several nodes of interaction have been identified between FoxO transcription factors and p53, a major tumor suppressor in humans and mice. However, the extent and importance of the...

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Bibliografiske detaljer
Main Authors: Renault, Valérie M., Thekkat, Pramod U., Hoang, Kimmi L., White, Jamie L., Brady, Colleen A., Broz, Daniela Kenzelmann, Venturelli, Ophelia S., Johnson, Thomas M., Oskoui, Philip R., Xuan, Zhenyu, Santo, Evan E., Zhang, Michael Q., Vogel, Hannes, Attardi, Laura D., Brunet, Anne
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136551/
https://ncbi.nlm.nih.gov/pubmed/21423206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.35
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