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The pro-longevity gene FoxO3 is a direct target of the p53 tumor suppressor

FoxO transcription factors play a conserved role in longevity and act as tissue-specific tumor suppressors in mammals. Several nodes of interaction have been identified between FoxO transcription factors and p53, a major tumor suppressor in humans and mice. However, the extent and importance of the...

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Detalhes bibliográficos
Main Authors: Renault, Valérie M., Thekkat, Pramod U., Hoang, Kimmi L., White, Jamie L., Brady, Colleen A., Broz, Daniela Kenzelmann, Venturelli, Ophelia S., Johnson, Thomas M., Oskoui, Philip R., Xuan, Zhenyu, Santo, Evan E., Zhang, Michael Q., Vogel, Hannes, Attardi, Laura D., Brunet, Anne
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136551/
https://ncbi.nlm.nih.gov/pubmed/21423206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.35
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