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The pro-longevity gene FoxO3 is a direct target of the p53 tumor suppressor
FoxO transcription factors play a conserved role in longevity and act as tissue-specific tumor suppressors in mammals. Several nodes of interaction have been identified between FoxO transcription factors and p53, a major tumor suppressor in humans and mice. However, the extent and importance of the...
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| Main Authors: | , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3136551/ https://ncbi.nlm.nih.gov/pubmed/21423206 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.35 |
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